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Vitamin C + Vitamin B12 + Niacin – This trio of essential vitamins can provide direct erectile and sexual wellness support and numerous other benefits. Vitamin C may be vital to promoting the hormonal balance men need for optimal sexual wellness. A 2024 study of 302 men suffering from fertility issues concluded higher vitamin C (ascorbic acid) intake was associated with improved androgen profiles. A 2021 study of 184 men suggested low vitamin B12 levels may contribute to erectile difficulties. A study including 160 men dealing with erectile problems reported participants ingesting niacin showed improved erectile parameters after 12 weeks. If you’re struggling with erectile issues, don’t give up. Check out the best gummies for ED (erectile difficulties). BioPerine: A US-patented bioavailability enhancer, BioPerine can boost the rate at which your body absorbs many nutrients. It delivers a standardized serving of 95% concentrated piperine. A molecule found in black pepper, piperine, can increase the activity of nutrient transporters. That means you should be able to derive more nutritional value from the potent ingredients in VigRX Plus.